Bioorganic and medicinal chemistry letters p. 749 - 754 (1999)
Update date:2022-08-04
Topics:
Parmee
Naylor
Perkins
Colandrea
Ok
Candelore
Cascieri
Deng
Feeney
Forrest
Hom
MacIntyre
Miller
Stearns
Strader
Tota
Wyvratt
Fisher
Weber
Human beta3 adrenergic receptor agonists containing 5-membered ring ureas were shown to be potent partial agonists with excellent selectivity over beta1 and beta2 binding. L-760,087 (4a) and L-764,646 (5a) (beta3 EC50 = 18 and 14 nM, respectively) stimula
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