The Lithium Diisopropylamide-induced Fragmentation of 1,3-Dithiolane Derivatives of Several Ketones Having α-Hydrogen

Article abstract of DOI:10.1246/bcsj.56.2537

The reaction of 1,3-dithiolane derivatives of ketones having a-hydrogen with lithium diisopropylamide results in fragmentation to the corresponding thioketone followed by further conversion in a few steps to the other intermediate species which, on trapping with alkyl halide, leads to a vinylic sulfide and/or a sulfide bearing a secondary alkyl group.