Tetrahedron Letters p. 3339 - 3342 (1999)
Update date:2022-08-02
Topics: Synthesis Catalyst Solvent Chromatography Extraction Reactant
Snider, Barry B.
Ahn, Yong
Foxman, Bruce M.
The tricyclic triamine core 27 of martinellic acid (2) has been prepared stereospecifically in eight steps from 2-hydroxymethylaniline in 11% overall yield. The key steps are the addition of 2-hydroxymethylaniline to vinylcyclopropane 14 to prepare cycloaddition precursor 19 in only two steps and an intramolecular [3+2] azomethine ylide cycloaddition reaction to produce tetracycle 20 with >9:1 diastereoselectivity.
View MoreShanghai Mio Chemical Co., Ltd
Contact:0086 21- 64401188-622
Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
Contact:852-27701081
Address:Room 2509, New Tech Plaza, 34 Tai Yau St., San Po Kong, HK
website:http://www.mingchem.com/en/index
Contact:0519-85170101-802
Address:Fifth Floor,B of Beihua Buliding,520 Road of Science and Education City,Changwu middle road NO.801,Wujin District,Changzhou,Jiangsu province
Xi'an Tizan Tech & Industry Co., Ltd.
Contact:86-18629066522
Address:C3009 TANG FENG INTERNATIONAL PLAZA, NO.18 FENGHUI NAN ROAD, XI'AN HIGH TECH ZONE, 710075 CHINA.
Shanghai Yuantai Chemical Products Co., Ltd
Contact:021--66129803
Address:Chengyin Road,Shanghai,China
Doi:10.1021/acs.jmedchem.8b01413
(2019)Doi:10.1007/BF00513425
(1982)Doi:10.1021/ja01049a016
(1969)Doi:10.1021/jo01018a019
(1965)Doi:10.1016/j.tet.2018.05.066
(2018)Doi:10.1016/S0008-6215(00)82130-8
(1969)
