Solid-phase synthesis of hydroxamic acid based TNF-α convertase inhibitors

DOI: 10.1016/S0040-4020(99)00347-6

Source and publish data:

Tetrahedron p. 7221 - 7232 (1999)

Update date:2022-08-02

Topics:

Authors:

Barlaam, Bernard

Koza, Patrice

Berriot, Julien

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(99)00347-6

An acid-sensitive linker for the solid phase synthesis of hydroxamic acids is described. Hydroxamic acid based TNFα inhibitors have been prepared by solid phase synthesis: derivatisation of N²-[4-(N-oxyamino)-2R-isobutyl- 3S-aminosuecinyl]-L-te

Full text of DOI:10.1016/S0040-4020(99)00347-6

Products guided by the article

Product name:[(1S,2R)-1-(2,4-Dimethoxy-benzyloxycarbamoyl)-2-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-methyl-pentyl]-carbamic acid 9H-fluoren-9-ylmethyl ester

Cas No:233749-49-0

R&D Labs maybe for 233749-49-0

Naturalin Bio-Resource Co., Ltd

website:http://www.naturalin.com

Contact:+86-0731-84430651

Address:B1-402, Lu-Valley Enterprise Square.No.27 Wenxuan Road. Lu-Valley Hi-Tech District.
Hangzhou Donglou Bio-nutrient Co., Ltd.

Contact:+86-571-82225795,13967112289

Address:Louta Town, Xiaoshan,Hangzhou,Zhejiang
JinTan Pingsheng Chemical Co.,Ltd

Contact:+86-519-82828200

Address:NO.11Danfengxilu Road,Jintan City,Jiangsu,China
NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD

Contact:86-0951-7815345

Address:North side of Qiyuan Road, west side of Yuanfeng Highway, New Material Park, Ningdong Energy and Chemical Industry Base, Ningxia,China
Huangshan Violet Biological Technology Co., Ltd

Contact:+86-559-2335676

Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China

Relevant to this article

Very stable phosphiranes

Doi:10.1002/(SICI)1521-3773(19990601)38:11<1623::AID-ANIE1623>3.0.CO;2-K
(1999)
4,5-O-Substituted Phenanthrenes from Cyclophanes. The Total Synthesis of Cannithrene II

Doi:10.1021/jo00213a008
(1985)
Synthesis of lyoniresinol with combined utilization of synthetic chemistry and biotechnological methods

Doi:10.1248/cpb.54.226
(2006)
Photoconductivity of liquid crystalline derivatives of pyrene and carbazole

Doi:10.1039/b612253a
(2007)
A NEW ALDOL REACTION VIA CERIUM ENOLATES

Doi:10.1016/S0040-4039(00)88405-1
(1983)
A Highly Efficient and General Synthetic Route to Optically Active Sulfinates; Stereospecyfic Boron Trifluoride Etherate-Catalyzed Esterification of Sulfinamides

Doi:10.1055/s-1983-30620
(1983)

Article Doi