Journal of the Chemical Society. Perkin transactions I p. 2951 - 2955 (1990)
Update date:2022-08-02
Topics:
Bloodworth, A. J.
Courtneidge, J. L.
Curtis, Richard J.
Spencer, Michael D.
Unsaturated hydroperoxides (R1R2CHO2H), 2-phenylpent-4-enyl hydroperoxide (1), 3-phenylhex-5-en-2-yl hydroperoxide (2), 5-methylhex-5-en-2-yl hydroperoxide (3), cyclo-oct-4-enyl hydroperoxide (18), and cyclo-oct-3-enyl hydroperoxide (24) have each been prepared from the corresponding carbonyl compound (R1R2CO) by the sequence: i, conversion to the p-tosylhydrazone (R1R2C=N-NHTs); ii, reduction with sodium cyanoborohydride at pH 3.5 to give the N'-p-tosylhydrazine (R1R2CH-NH-NHTs); and iii, oxidation with hydrogen peroxide and sodium peroxide.Isomerisation occurs in the preparation of the cyclo-octenyl hydroperoxides, particuarly if the pH falls markedly below 3.5 in the reduction step.
View MoreHuangshan Honghui Pharm Technology Co., Ltd.(expird)
website:http://www.honghuichem.com
Contact:18855958372
Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province
Shanghai Sinofluoro Scientific Co., Ltd
Contact:+86-21-64279360
Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,
Wuhan Chemwish Technology Co., Ltd
website:http://www.chemwish.com/
Contact:+86-27-67849912
Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei，P.R. China
website:https://sdjingyuan.lookchem.com/
Contact:86-531-82687998
Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China
TAIZHOU XINGCHENG CHEMPHARM CO.,LTD.
Contact:0086-0576-88551200,88886292 ,88880039
Address:B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China
Doi:10.1021/ja01590a047
(1956)Doi:10.1016/S0039-128X(00)00149-5
(2001)Doi:10.1002/(SICI)1522-2675(19990609)82:6<909::AID-HLCA909>3.0.CO;2-T
(1999)Doi:10.1021/np980521o
(1999)Doi:10.1007/s00044-017-1815-z
(2017)Doi:10.1016/S0040-4039(01)88114-4
(1969)
