Isolation and synthesis of a novel immunosuppressive 17α- substituted dammarane from the flour of the Palmyrah palm (Borassus flabellifer)

Article abstract of DOI:10.1016/S0960-894X(99)00220-6

The novel triterpene 1 with a dammarane skeleton and a hitherto unknown 17α-substitution pattern has been isolated from the Palmyrah palm in low yield and prepared by synthesis in larger quantities. 1 was shown to be an extremely potent immunosuppressant