A new protecting group strategy for amino groups in oligonucleotide chemistry: CEOC group

Article abstract of DOI:10.1080/07328319908044661

A new protecting group, 2-cyanoethyloxycarbonyl, or CEOC, has been developed for amino groups and utilized in synthesizing modified oligonucleotides. (CEOC)-oxy-succinimide reagent has been synthesized to introduce this protecting group. The protecting gr

Full text of DOI:10.1080/07328319908044661

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A New Protecting Group Strategy
for Amino Groups in Oligonucleotide
Chemistry: CEOC Group
Muthiah Manoharan a , Thazha P. Prakash a , Isabelle Barber-peoc'h
a , Balkrishen Bhat a , Guillermo Vasquez a , Bruce S. Ross a & P. Dan
Cook a
a Department of Medicinal Chemistry, Isis Pharmaceuticals, 2292
Faraday Avenue, Carlsbad, CA, 92008, USA
Published online: 04 Oct 2006.
To cite this article: Muthiah Manoharan , Thazha P. Prakash , Isabelle Barber-peoc'h , Balkrishen
Bhat , Guillermo Vasquez , Bruce S. Ross & P. Dan Cook (1999): A New Protecting Group Strategy
for Amino Groups in Oligonucleotide Chemistry: CEOC Group, Nucleosides and Nucleotides, 18:6-7,
1199-1201
To link to this article: http://dx.doi.org/10.1080/07328319908044661
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