Synthesis of pyrrolidine or piperidine ring-fused azepino[5,4,3- cd]indole derivatives

Article abstract of DOI:10.1016/S0040-4039(99)01076-X

The synthesis of pyrrolidine or piperidine ring-fused 2-phenyl- azepino[5,4,3-cd]indole derivatives (2) has been accomplished through the N- acyliminium ion cyclization of hydroxy- or alkoxylactams (5) derived from cyclic anhydrides or chiral hydroxy acids.