Synthesis and applications of fluorous silyl protecting groups with improved acid stability

DOI: 10.1016/S0040-4039(99)01106-5

Source and publish data:

Tetrahedron Letters p. 5667 - 5670 (1999)

Update date:2022-08-03

Topics:

Authors:

Roever, Stephan

Wipf, Peter

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Article abstract of DOI:10.1016/S0040-4039(99)01106-5

Fluorous alkoxysilyl protecting groups have been developed and evaluated for their acid stability. tert-Butylphenyl-1H,1H,2H,2H-heptadecafluorodecyloxysilyl (BPFOS) ethers in particular were found to be surprisingly acid stable and allow simple protection-purification-deprotection schemes by liquid-liquid extraction with FC-72/CH₃CN or by solid phase extraction with fluorous reverse phase silica gel.

Full text of DOI:10.1016/S0040-4039(99)01106-5

Products guided by the article

Product name:tert-butyl-phenyl-1H,1H,2H,2H-heptadecafluorodecyloxysilyl bromide

Cas No:243645-01-4

R&D Labs maybe for 243645-01-4

Weihao Chemtech (ChangZhou) Co., Ltd.(expird)

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Address:NO 217 huangshan Rd ,Changzhou
Shanghai Balmxy Pharmaceutical Co., Ltd

Contact:0086-21-24206007

Address:Room 402, 15#, No. 909 wangyue Road, shanghai, P. R. China
Changzhou Kingyo Chemical Corporation Ltd.

website:http://www.kingyochem.com

Contact:+86-519-85105717

Address:19# Wuqing North Road, Changzhou , Jiangsu, China
Chengdu Green Young Biopharmaceutical INC

Contact:+86-28-85337952

Address:1-B-26,Tianhe Industry Park, No.1480 of Tianfu Road,Chengdu,P.R.China,610000
Joyochem Co., Ltd.

website:https://sdjingyuan.lookchem.com/

Contact:86-531-82687998

Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China

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