Tetrahedron Letters p. 6749 - 6752 (1999)
Update date:2022-08-04
Topics:
Hendrix, James A.
Stefany, David W.
A mild reduction of ortho-fluoro benzamides was discovered using LAH. The reaction proceeds cleanly and in moderate yields. The scope of the reaction is explored and a mechanism is proposed. A two carbon spacer between the amide and a 3°amine is optimal for this chelation controlled reaction.
View MoreShandong Jiulong Hisince Pharmaceutical Co.,Ltd.
Contact:+86-15853188990
Address:Huadian Pioneer Park, Huadian Township, Qihe County, Dezhou City, Shandong, P.R.China
Contact:+86-28-88523492
Address:714rooms of Time Square, Pujiang County
Hangzhou LINGEBA Technology Co., Ltd.
Contact:+0086-571-87389059
Address:Office 1-913,NewYouth Plaza, GongShu Area, HangZhou,ZheJiang,P.R.China
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
website:http://www.shydtec.com
Contact:86-21-57721279
Address:Science and Technology Park, Songjiang District, Shanghai, China
QINGDAO ON-BILLION INDUSTRAIL CO.,LTD
website:http://www.obn.com.cn
Contact:+86-15005320811 +86-532-80681989
Address:F35 Parkson Mansion No.44-60 Zhongshan Rd.
Doi:10.1021/acscatal.7b01669
(2017)Doi:10.1016/S0040-4039(99)01418-5
(1999)Doi:10.1055/s-0028-1088116
(2009)Doi:10.1021/ja01048a027
(1969)Doi:10.3390/molecules21091257
(2016)Doi:10.1055/s-1999-2858
(1999)