A novel approach for the synthesis of 5-substituted tetrazole derivatives from primary amides in mild one-step method

DOI: 10.1016/S0040-4039(97)00052-X

Source and publish data:

Tetrahedron Letters p. 1257 - 1260 (1997)

Update date:2022-07-30

Topics:

Authors:

El-Ahl, Abdel-Aziz S.

Elmorsy, Saad S.

Elbeheery, Akram H.

Amer, Fathy A.

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Article abstract of DOI:10.1016/S0040-4039(97)00052-X

A new mild one-step method for the conversion of primary acid amides to 5-substituted tetrazoles in nearly quantitative yields employing triazidochlorosilane (TACS) is reported.

Full text of DOI:10.1016/S0040-4039(97)00052-X

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