
Tetrahedron Letters p. 7385 - 7388 (1999)
Update date:2022-08-03
Topics:
Ichikawa, Eiko
Yamamura, Shosuke
Kato, Kuniki
The enantiomerically pure synthesis of 9-[(1'R,2'R,3'S)-bis(hydroxymethyl)thietan-1'-yl]adenine 2, 3'-thio analog of oxetanocin A, was achieved via coupling with sulfoxide 17 and 6-chloropurine in the presence of TMSOTf and Et3N under the Pummerer reaction conditions.
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Doi:10.1021/jo00826a048
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