Synthesis of iodoaminoimidazole arabinoside (IAIA): A potential reductive metabolite of the spect imaging agent, iodoazomycin arabinoside (IAZA)

Article abstract of DOI:10.1080/07328319908044860

The stereospecific synthesis of 1-(5-deoxy-5-iodo-α-D- arabinofuranosyl)-2-aminoimidazole (iodoaminoimidazole arabinoside: IAIA, 2) is described. The reaction of the protected sugar bromide (8) and trifluoroacetamidoimidazole (10B) gave the coupled produc

Full text of DOI:10.1080/07328319908044860

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Synthesis of Iodoaminoimidazole
Arabinoside (IAIA): A Potential Reductive
Metabolite of the Spect Imaging Agent,
Iodoazomycin Arabinoside (IAZA)
Herbert C. Lee a , Piyush Kumar a , Leonard I. Wiebe a , Robert
McDonald b , John R. Mercer a , Kazue Ohkura c & Koh-Ichi Seki c
a Faculty of Pharmacy and Pharmaceutical Sciences
b Department of Chemistry , University of Alberta , Edmonton,
Alberta, Canada , T6G 2E1
c Faculty of Pharmaceutical Sciences , Health Sciences University of
Hokkaido , Ishikari-Tobetsu, Hokkaido, Japan , 061-0293
Published online: 04 Oct 2006.
To cite this article: Herbert C. Lee , Piyush Kumar , Leonard I. Wiebe , Robert McDonald , John R.
Mercer , Kazue Ohkura & Koh-Ichi Seki (1999) Synthesis of Iodoaminoimidazole Arabinoside (IAIA):
A Potential Reductive Metabolite of the Spect Imaging Agent, Iodoazomycin Arabinoside (IAZA),
Nucleosides and Nucleotides, 18:9, 1995-2016, DOI: 10.1080/07328319908044860
To link to this article: http://dx.doi.org/10.1080/07328319908044860
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