Solid phase synthesis of highly substituted 2,4-dioxopiperidines

DOI: 10.1016/S0040-4039(99)01499-9

Source and publish data:

Tetrahedron Letters p. 7185 - 7188 (1999)

Update date:2022-07-30

Topics:

Authors:

Chai, Wenying

Murray, William V.

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Article abstract of DOI:10.1016/S0040-4039(99)01499-9

A convenient solid phase synthesis of (E)-N-substituted-acetyl-N-(2-methoxycarbonyl-3-(aryl)-prop-2-enyl)amino acids and the condensation of their esters to highly substituted 2,4-dioxopiperidines are described.

Full text of DOI:10.1016/S0040-4039(99)01499-9

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Product name:4-{(E)-3-[(1-Carboxy-ethyl)-(2-ethoxycarbonyl-acetyl)-amino]-2-methoxycarbonyl-propenyl}-benzoic acid methyl ester

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