Synthesis of novel orthoalkylaminophenol derivatives as potent neuroprotective agents in vitro.

DOI: 10.1016/S0960-894X(99)00504-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2929 - 2934 (1999)

Update date:2022-08-04

Topics:

Authors:

Larget, Ronan

Lockhart, Brian

Pfeiffer, Bruno

Neudorffer, Anne

Fleury, Maurice-Bernard

Largeron, Martine

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Article abstract of DOI:10.1016/S0960-894X(99)00504-1

A series of orthoalkylaminophenol derivatives was synthesized and tested in vitro with respect to their neuroprotective effect. Some of these compounds exhibited a potent antioxidant activity close to that of standard α-tocopherol.

Full text of DOI:10.1016/S0960-894X(99)00504-1

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