3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists

DOI: 10.1016/j.bmcl.2005.03.086

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2553 - 2557 (2005)

Update date:2022-09-26

Topics:

Authors:

Neel, David A.

Brown, Matthew L.

Lander, Peter A.

Grese, Timothy A.

Defauw, Jean M.

Doti, Robert A.

Fields, Todd

Kelley, Sally Ann

Smith, Stephon

Zimmerman, Karen M.

Steinberg, Mitchell I.

Jadhav, Prabhakar K.

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Article abstract of DOI:10.1016/j.bmcl.2005.03.086

Syntheses and SAR studies of 3,3-bisaryloxindole analogues provided potent mineralocorticoid receptor (MR) antagonists that were selective over other steroid nuclear hormone receptors.

Full text of DOI:10.1016/j.bmcl.2005.03.086

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