Asymmetric synthesis of syn hydroxyphenylalanine via aziridine ring expansion to an oxazoline

DOI: 10.1016/S0040-4039(99)01734-7

Source and publish data:

Tetrahedron Letters p. 8261 - 8264 (1999)

Update date:2022-08-03

Topics:

Authors:

Cardillo, Giuliana

Gentilucci, Luca

Tolomelli, Alessandra

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Article abstract of DOI:10.1016/S0040-4039(99)01734-7

The synthesis of (2R,3S)- and (2S,3R)-hydroxyphenylalanine is reported. The main steps are the 1,4-addition of O-benzylhydroxylamine to unsaturated imides and the ring expansion of trans-aziridines.

Full text of DOI:10.1016/S0040-4039(99)01734-7

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