Oxazaborolidine catalyzed enantioselective reductions of cyclic meso-imides

DOI: 10.1016/S0040-4039(00)79972-2

Source and publish data:

Tetrahedron Letters p. 1087 - 1090 (1994)

Update date:2022-08-05

Topics:

Authors:

Romagnoli, Romeo

Roos, Eric C.

Hiemstra, Henk

Moolenaar, Marinus J.

Nico Speckamp

Kaptein, Bernard

Schoemaker, Hans E.

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Article abstract of DOI:10.1016/S0040-4039(00)79972-2

A new asymmetric reduction method for meso-imides is reported. Treatment of various imides with a mixture of a chiral oxazaborolidine and BH₃ leads to a mixture of cis- and trans-hydroxylactams and, after subsequent ethanolysis, to the correspo

Full text of DOI:10.1016/S0040-4039(00)79972-2

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