A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4'-(3-diethylaminopropoxy)-phenyl]-benzofuran.

Article abstract of DOI:10.1016/S0040-4039(99)02030-4

A short and convenient synthesis of 3-p-toluoyl-2-[4'-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid, which is thought to be the underlying cause of Alzheimer's disease, is described.