1-(2-methoxyphenyl)-4-alkylpiperazines: Effect of the N-4 substitutent on the affinity and selectivity for dopamine D4 receptor

DOI: 10.1016/S0960-894X(97)00218-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1327 - 1330 (1997)

Update date:2022-08-03

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Authors:

Perrone, Roberto

Berardi, Francesco

Colabufo, Nicola A.

Leopoldo, Marcello

Tortorella, Vincenzo

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Article abstract of DOI:10.1016/S0960-894X(97)00218-7

Binding data on dopaminergic D₂ and D₆ and adrenergic eel receptors of nine methoxyphenyl)piperazine derivatives are reported. The benzamide derivative 11 and ketone 12 displayed the highest affinity for human cloned D₄ re

Full text of DOI:10.1016/S0960-894X(97)00218-7

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