Analytical Chemistry p. 1965 - 1970 (1994)
Update date:2022-08-02
Topics:
Dasgupta, Purnendu K.
Zhang, Genfa
Schulze, Shawn
Marx, John N.
The standard procedure for determining carbonyl compounds involves the addition of strong caustic alkali to 2,4-dinitrophenylhydrazones formed upon the reaction of carbonyl compounds with 2,4-dinitrophenylhydrazine (DNPH).1 In strong base, the hydrazones form a dark red anion of quinonoid structure,2 while the corresponding product from the unreacted DNPH decomposes rapidly, resulting in a low blank. The mechanism of this decomposition has never been clearly understood. In this work, we describe a photometric flow injection analyzer for the automated measurement of the carbonyl content of alcohol ethoxylate samples. A detailed study of the mechanism of the alkaline decomposition is reported. Parameters affecting the performance of the automated system were studied. The final system attained nearly equivalent responses of C2-C9 aliphatic carbonyl compounds (within ± 12%), a sample throughput of 20 h-1, a limit of detection of 0.5 mg/L>C=O, and response linearity over 2 orders of magnitude. The method was applied to industrial samples, and the results compared well with those from the manual standard method. It should be applicable for the measurement of the carbonyl content in a variety of other organic matrices.
View MoreContact:+86-20-32051076
Address:1105,Building A, International Business Incubator,Science City
Sichuan Highlight Fine Chemicals Co., Ltd.
Contact:+86-28-8525 1605
Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section
website:http://www.weichichem.com
Contact:+8613912949432
Address:Fine Chemical Industrial Base,Wujiang town,He County,Anhui China.
Zhejiang Tianyu Pharmaceutical Co., Ltd.
Contact:+86-576-84177669, 89189665,89189688,84168770
Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Contact:86-571-86737118-8689
Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Doi:10.1016/S0040-4039(99)02190-5
(2000)Doi:10.1021/jo991681n
(2000)Doi:10.1128/AAC.03543-14
(2015)Doi:10.1021/ja065042n
(2006)Doi:10.1002/hlca.19600430137
(1960)Doi:10.1021/ol062576k
(2006)