Potassium Borohydride Reductions of Ketones absorbed into Polymer Supports: Stereochemical Effects

Article abstract of DOI:10.1039/c39880000310

The proportions of 6α-alcohol obtained from aqueous potassium borohydride reductions of 3β-cholestan-6-one (1) absorbed into various polymers varied from 0 to 90percent depending on the polymer used and whether or not a phase transfer catalyst was added; some other ketones show similar streochemical effects, the greatest effects probably arising when the substrates are adsorbed to the inner surfaces of appropriate polymers.