
Heterocyclic Communications p. 593 - 598 (2003)
Update date:2022-08-02
Topics:
Petrova, Katia
Petrov, Ognyan
Antonova, Antonina
Kalcheva, Veneta
Derivatives of a new type tricyclic system having a 1,4-benzothiazine skeleton are described. The reaction of 1-(2-mercaptophenyl)-2H-imidazol-2-ones 2 with excess formaldehyde in acid medium resulted in the formation of 2,4-dihydro-1H-imidazo[5,1-c][1,4]benzothiazin-1-one 3. The starting compounds 2 were prepared by a modification of a previously described method of ring transformation of 3-(2-oxopropyl)-2(3H)-benzothiazolones in reactions with primary amines.
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