Artificial oligonucleotides consisting of an analog of nucleoside antibiotics, carbocyclic oxetanocins1

Article abstract of DOI:10.1016/S0040-4039(99)01410-0

Modified oligonucleotides, hexadecamers, containing carbocyclic analogues of oxetanocin A and T, have been synthesized from the corresponding chiral carbocyclic nucleosides. The oligonucleotide derived from carbocyclic oxetanocin A forms a stable triple-helix with uridine oligoribonucleotide even under physiological conditions.