Artificial oligonucleotides consisting of an analog of nucleoside antibiotics, carbocyclic oxetanocins1

DOI: 10.1016/S0040-4039(99)01410-0

Source and publish data:

Tetrahedron Letters p. 6835 - 6840 (1999)

Update date:2022-08-05

Topics:

Authors:

Katagiri, Nobuya

Morishita, Yoshihiro

Oosawa, Iichiro

Yamaguchi, Masahiko

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Article abstract of DOI:10.1016/S0040-4039(99)01410-0

Modified oligonucleotides, hexadecamers, containing carbocyclic analogues of oxetanocin A and T, have been synthesized from the corresponding chiral carbocyclic nucleosides. The oligonucleotide derived from carbocyclic oxetanocin A forms a stable triple-helix with uridine oligoribonucleotide even under physiological conditions.

Full text of DOI:10.1016/S0040-4039(99)01410-0

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