
Tetrahedron Letters p. 6835 - 6840 (1999)
Update date:2022-08-05
Topics:
Katagiri, Nobuya
Morishita, Yoshihiro
Oosawa, Iichiro
Yamaguchi, Masahiko
Modified oligonucleotides, hexadecamers, containing carbocyclic analogues of oxetanocin A and T, have been synthesized from the corresponding chiral carbocyclic nucleosides. The oligonucleotide derived from carbocyclic oxetanocin A forms a stable triple-helix with uridine oligoribonucleotide even under physiological conditions.
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