Journal of labelled compounds and radiopharmaceuticals p. 113 - 120 (2000)
Update date:2022-08-04
Topics:
Moenius
Andres
Acemoglu
Kohler
Schnelli
Zueger
RAD001 2, a new immunosuppressant, was labelled in its hydroxyethyl side chain as well as in the rapamycin skeleton using carrier-free lithium triethylborotritide and tributyltin tritide (TBTT), respectively. The tritium labelling of the rapamycin moiety followed Curran's strategy of intramolecular hydrogen transfer. Our studies demonstrated that base-free TBTT is essential for a successful reaction.
View Morewebsite:https://www.yacoo.com.cn/en/
Contact:86-512-87182055
Address:No.112 Xinqing Rd, Suzhou Industrial Park, China, 215125, China
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd
Contact:+86 411 84674606
Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
Shanghai Sungo Technology Chemical Co., Ltd
Contact:0086-21-51385579
Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Daicel Chiral Technologies (China)CO.,LTD
Contact:021-5046-0086*8
Address:Part C, FL 5, the 16th Building, No. 69, XiYa Road, WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R.China
website:http://www.uvchemkeys.com
Contact:0086-021-58785816
Address:RM2607 Building No.1 Guosheng, Lane 388, Zhongjiang Road, Putuo District, Shanghai 200062 China
Doi:10.1002/zaac.19703770106
(1970)Doi:10.1016/S0040-4020(00)00160-5
(2000)Doi:10.1016/S0960-894X(00)00138-4
(2000)Doi:10.1055/s-1970-21615
(1970)Doi:10.1016/j.ica.2010.06.020
(2010)Doi:10.1021/ic034699w
(2003)
