Lithium-salt effects in peptide synthesis. Part I: Conditions for the use of lithium-salts in coupling reactions

DOI: 10.1002/hlca.19910740319

Source and publish data:

Helvetica Chimica Acta p. 617 - 627 (1991)

Update date:2022-08-04

Topics: Peptide Synthesis Conditions Coupling reactions Experimental

Authors:

Thaler, Adrian

Seebach, Dieter

Cardinaux, Francis

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Article abstract of DOI:10.1002/hlca.19910740319

The influence of Li-salts on the course of peptide-coupling reactions was investigated. As a model for segment couplings, Ac-Phe-OH was coupled to HCl . H-Ala-OMe using the mixed anhydride, DCCl, DCCl/HOBt, BOPCastro and TBTU-Knorr methods. As a model for

Full text of DOI:10.1002/hlca.19910740319

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