Hydrogen Bond Equilibra of Phenol-Pyridine in Cyclohexane, CCl4 and Benzene Solvents

Article abstract of DOI:10.1021/j100290a076

Phenol-pyridine enthalpies and free energies of hydrogen bond formation in cyclohexane, CCl4, and benzene solvents have been determined by calorimetric measurements.Schematic mapping techniques show that only 1:1 phenol-pyridine complexes exist in solution under the experimental conditions used.The enthalpy differences in the three solvents are explained in terms of dipolar and specific interactions of the acid base with solvent.