Tetrahedron p. 5031 - 5038 (1985)
Update date:2022-08-03
Topics:
Artaud, I.
Torossian, G.
Viout, P.
Dehydrated solid KOH, suspended in aprotic solvents, is used as a base for ketone and aldehyde alkylation.The best solvent as regards yields and selectivity is DME.The quantity of KOH depends on the carbonyl compound acidity.This method gives as good results as less convenient homogeneous conditions.
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