Free radical cyclizations leading to four-membered rings. I. Betalactam production using tributyltin hydride

DOI: 10.1016/S0040-4039(00)79917-5

Source and publish data:

Tetrahedron Letters p. 2335 - 2338 (1991)

Update date:2022-07-31

Topics:

Authors:

Fremont, Susan L.

Belletire, John L.

Ho, Douglas M.

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Article abstract of DOI:10.1016/S0040-4039(00)79917-5

Use of HSnBu₃ for the reductive cyclization of suitable enamides having a bromide substituent alpha to the carbonyl group affords beta-lactams in good yields.

Full text of DOI:10.1016/S0040-4039(00)79917-5

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