Rational design of a new series of mixed anti-HIV pronucleotides

DOI: 10.1016/S0960-894X(98)00535-6

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3003 - 3006 (1998)

Update date:2022-09-26

Topics:

Authors:

Schlienger, Nathalie

Beltran, Thierry

Perigaud, Christian

Lefebvre, Isabelle

Pompon, Alain

Aubertin, Anne-Marie

Gosselin, Gilles

Imbach, Jean-Louis

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00535-6

MonoSATE aryl phosphotriesters of AZT are able to deliver intracellularly the corresponding 5'-mononucleotide. This process requires activation by an esterase followed by a phosphodiesterase. This finding opens the way to the design of new pronucleotide s

Full text of DOI:10.1016/S0960-894X(98)00535-6

Products guided by the article

Product name:O-(N^α-tert-butoxycarbonyl-L-tert-butoxytyrosinyl) O-(S-pivaloyl-2-thioethyl) 3'-azido-2',3'-deoxythymidin-5'-yl phosphate

Cas No:312750-67-7

R&D Labs maybe for 312750-67-7

Nanjing Capatue Chemical Co., Ltd

Contact:+86-25-86371192 +86-025-85720158

Address:No.20 Jiangjun Avenue, Jiangning Economic & Technical Development Zone
SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Shanghai PotentPharm Science and Technology Co.,Ltd

Contact:86-021-51969655

Address:Unit B, Building 18, No.300, Chuantu Rd,Pudong District, Shanghai 201202, China
Jai Radhe Sales

website:http://www.jairadhesales.com

Contact:0091-79-26431096

Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
sichuan tiancai fine co LTD.

website:http://www.tcfinechem.com/

Contact:18681346930

Address:baifu town,whou district

Relevant to this article

Delepine reaction with 2-aryl-4-chloromethyl-oxazoles. 15. Heterocyclic compounds

Doi:10.1002/ardp.19713040608
(1971)
Doi:10.1021/ja01102a515
(1953)
Synthesis of arylacetates from benzylic alcohols and oxalate esters through decarboxylative coupling

Doi:10.1002/chem.201301033
(2013)
Doi:10.1021/jm00283a004
(1971)
Synthetic studies toward the microtubule-stabilizing agent laulimalide: Synthesis of the C₁-C₁₄ fragment

Doi:10.1016/S0040-4039(00)02116-X
(2001)
Synthesis of 2-chloro-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one

Doi:10.1016/S0040-4039(00)02219-X
(2001)

Article Doi