Bioscience, Biotechnology and Biochemistry p. 2209 - 2215 (2000)
Update date:2022-08-04
Topics:
Yamauchi
Yamamoto
Kinoshita
(3R)-3-[(1R)-1-(tert-Butyldimethylsilyl)oxy-1-(2-methoxy-4,5-methylenedioxyphenyl) methyl]-2-methylene-4-butanolide, which is a key intermediate for the synthesis of 1,2-oxidized furofuran lignan, was stereoselectively synthesized from L-glutamic acid by applying direct methylenation to butanolide.
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