Enantioselective addition of 2-methyl-3-butyn-2-ol to aldehydes: Preparation of 3-hydroxy-1-butynes

DOI: 10.1021/ol006791r

Source and publish data:

Organic Letters p. 4233 - 4236 (2000)

Update date:2022-08-05

Topics:

Authors:

Boyall Boyall

López López

Sasaki Sasaki

Frantz Frantz

Carreira

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Article abstract of DOI:10.1021/ol006791r

(equation presented) We report the first example of enantioselective aldehyde additions of 2-methyl-3-butyn-2-ol, a commodity bulk chemical that is readily available. Following a facile fragmentation reaction, the addition reactions provide access to opti

Full text of DOI:10.1021/ol006791r

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