Journal of Antibiotics p. 1282 - 1292 (2000)
Update date:2022-08-03
Topics:
Berge
Broom
Houge-Frydrych
Jarvest
Mensah
McNair
O'Hanlon
Pope
Rittenhouse
SB-219383 is a naturally occurring antibiotic, which acts by inhibition of tyrosyl tRNA synthetase. Semi-synthetic derivatives of SB-219383 were prepared with the objective of elucidating the key features required for inhibition of tyrosyl tRNA synthetase in order to improve the antibacterial activity. Some ester and amide derivatives as well as monocyclic analogues exhibited sub-nanomolar inhibitory activity against tyrosyl tRNA synthetase.
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Doi:10.1055/s-0030-1259512
(2011)Doi:10.1021/ja00001a037
(1991)Doi:10.1039/c1cc10438a
(2011)Doi:10.1016/S0277-5387(00)83584-6
(1992)Doi:10.1055/s-0036-1588523
(2017)Doi:10.1002/cmdc.201000425
(2011)
