Tetrahedron Letters p. 3455 - 3456 (1999)
Update date:2022-08-05
Topics:
Bittner, Christian
Burgo, Andrea
Murphy, Patrick J.
Sung, Chi H.
Thornhill, Andrew J.
The reaction of Grignard reagents with α-hydroxy-γ-ketocarboxylic acids leads to the formation of tetrasubstituted γ-butyrolactones, one of which was converted into a bicyclic lactone 10 via consecutive bromoacetylation, Wittig cyclisation and hydrogenati
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