Journal of Organic Chemistry p. 12692 - 12702 (2020)
Update date:2022-07-30
Topics:
Grygorenko, Oleksandr O.
Chernykh, Anton V.
Olifir, Oleksandr S.
Kuchkovska, Yuliya O.
Volochnyuk, Dmitriy M.
Yarmolchuk, Vladimir S.
A series of all 12 cis- and trans-cyclopropanecarboxylic acids and cyclopropylamines bearing CH2F, CHF2, and CF3 substituents were synthesized by different methods on a multigram scale. Dissociation constants (pKa) and log P values were measured for the o
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