FACILE SYNTHESIS OF GRAMICIDIN S VIA CYCLIZATION OF A LINEAR PENTAPEPTIDE

DOI: 10.1016/S0040-4039(00)78991-X

Source and publish data:

Tetrahedron Letters p. 2179 - 2180 (1980)

Update date:2022-07-29

Topics:

Authors:

Minematsu, Joshihiro

Waki, Michinori

Suwa, Kazushi

Kato, Tetsuo

Izumiya, Nobuo

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Article abstract of DOI:10.1016/S0040-4039(00)78991-X

Azide and N-hydroxysuccinimide ester of five pentapeptides related to gramicidin S (cyclic decapeptide) were cyclized to determine the ratio of dimer to monomer in the cyclization product, the pentapeptide dervative with D-Phe as C-terminus giving the dimer in good yield.

Full text of DOI:10.1016/S0040-4039(00)78991-X

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