Synthesis of 2,6-disubstituted pyridines by lithiation of pyrazolo[1,5-a] pyridines

DOI: 10.1248/cpb.43.174

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 174 - 176 (1995)

Update date:2022-08-05

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Authors:

Miyashita

Sato Sato

Watanabe

Tanji Tanji

Higashino

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Article abstract of DOI:10.1248/cpb.43.174

Lithiation of 3-(4,4-dimethyl-2-oxazolin-2-yl)pyrazolo[1,5-a]pyridine (1a); with 2 molar equivalents of n-BuLi followed by reaction with benzaldehyde) yielded α-(4,4-dimethyl-2-oxazolidinylidene)-6-(α-hydroxybenzyl)- 2-pyridineacetonitrile (2a). Upon simi

Full text of DOI:10.1248/cpb.43.174

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