Reductive alkylations involving 2°- and 3°-enolyl adduct radicals

Article abstract of DOI:10.1016/S0040-4039(00)76681-0

Reductive tert-butylation of electronegatively substituted alkenes is readily achieved in Me₂SO by reaction with excess t-BuHgCl/Et₃SiH. Reactivity studies indicate that towards t-Bu^. s-cis enones are more reactive than the s-trans conformers.