
Journal of Pharmaceutical Sciences p. 627 - 631 (1989)
Update date:2022-08-04
Topics:
Largeron
Fleury
The pK(a) values of acid-base equilibria involved in the protonation of zopiclone and analogues are determined by UV-visible absorption spectrometry and pH-metry. Hydrogen ion catalysis is evidenced in the carbamate hydrolysis.
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