
Tetrahedron Letters p. 4323 - 4326 (1996)
Update date:2022-09-26
Topics:
Khau, Vien V.
Martinelli, Michael J.
Azomethine imines were generated in a controlled manner through a thermally allowed 1,3-dipolar cycloreversion of 1,3,4-oxadiazolidines and subsequently trapped with dipolarophiles. This method results in the construction of the pyrazolidine heterocycles. A new method for the selective formation of the key semicarbazide substrate, from benzylidene hydrazone, is also disclosed.
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