Trehalose-based neuroprotective autophagy inducers

DOI: 10.1016/j.bmcl.2021.127929

Source and publish data:

Bioorganic and Medicinal Chemistry Letters (2021)

Update date:2022-08-03

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Authors:

Arosio, Daniela

Assoni, Giulia

Colombo, Eleonora

Frapporti, Giulia

Gornati, Davide

Perez-Carrion, Maria Dolores

Piccoli, Giovanni

Polito, Laura

Seneci, Pierfausto

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Article abstract of DOI:10.1016/j.bmcl.2021.127929

A small set of trehalose-centered putative autophagy inducers was rationally designed and synthesized, with the aim to identify more potent and bioavailable autophagy inducers than free trehalose, and to acquire information about their molecular mechanism

Full text of DOI:10.1016/j.bmcl.2021.127929

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