Palladium-catalyzed intramolecular arylation of an anilide enolate, application to an efficient formal total synthesis of physovenine

DOI: 10.1016/S0040-4039(02)00059-X

Source and publish data:

Tetrahedron Letters p. 1363 - 1365 (2002)

Update date:2022-08-05

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Authors:

Zhang, Tony Y.

Zhang, Hongbin

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Article abstract of DOI:10.1016/S0040-4039(02)00059-X

An expedient formal total synthesis of the calabar alkaloid physovenine was reported. The key step involves an oxindole synthesis via palladium-catalyzed intramolecular arylation of o-bromoanilide.

Full text of DOI:10.1016/S0040-4039(02)00059-X

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