Journal of Organic Chemistry p. 8023 - 8030 (2017)
Update date:2022-07-31
Topics:
Liu, Rui
Yang, Zhenyu
Ni, Yuxin
Song, Kaixuan
Shen, Kai
Lin, Shaohui
Pan, Qinmin
Pd(II)/bipyridine-catalyzed conjugate addition of arylboronic acids to α,β-unsaturated carboxylic acids (including β,β-disubstituted acrylic acids) was developed and optimized, which provided a mild and convenient method for the highly challenging synthesis of β-quaternary carbons substituted carboxylic acids.
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