Tetrahedron Letters p. 2835 - 2838 (2002)
Update date:2022-08-05
Topics:
Sun, Haiying
Bapu Reddy, Gaddam
George, Clifford
Meuillet, Emmanuelle J.
Berggren, Margareta
Powis, Garth
Kozikowski, Alan P.
Two 3-hydroxy(phosphono)methyl-bearing phosphatidylinositol ether lipid analogues were synthesized and shown to be inhibitors of Akt and PI3-K. These compounds were also shown to inhibit the growth of HT-29 human colon cancer cells and MCF-7 human breast
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