Journal of Medicinal Chemistry p. 1290 - 1295 (1992)
Update date:2022-09-26
Topics: Antagonist Lipophilicity IC50 Pharmacophore binding affinity Steric Effects Structure-Activity Relationship (SAR) Cyclohexyl Agonist Muscarinic receptor Selectivity Index Ki (Inhibition constant)
Leader, Haim
Gordon, Richard K.
Baumgold, Jesse
Boyd, Victoria L.
Newman, Amy H.
et al.
A series of aprophen <(N,N-diethylamino)ethyl 2,2-diphenylpropionate> analogues, called cylexphenes, were synthesized with alterations in (1) the chain length of the amine portion of the ester, (2) the alkyl groups on the amino alcohol and (3) a cyclohexy
View MoreWuhan Chemwish Technology Co., Ltd
website:http://www.chemwish.com/
Contact:+86-27-67849912
Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei，P.R. China
Contact:86-512-69362780,69362785
Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
QINGDAO ON-BILLION INDUSTRAIL CO.,LTD
website:http://www.obn.com.cn
Contact:+86-15005320811 +86-532-80681989
Address:F35 Parkson Mansion No.44-60 Zhongshan Rd.
Changsha Yonta Industry Co., Ltd.
Contact:+ 86-731-8535 2228
Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
KA-SHING Business Trade Macau Co., Ltd.
Contact:00853-28430045
Address:23rd Floor, Block 3 La Cite, Areia Preta, Macao
Doi:10.1002/ejoc.201701235
(2017)Doi:10.1080/00397910500182606
(2005)Doi:10.1021/jo0355799
(2004)Doi:10.1021/ja020816v
(2002)Doi:10.1016/S0040-4020(01)93888-8
(1965)Doi:10.1021/acs.biochem.9b00003
(2019)
