Journal of Medicinal Chemistry p. 1290 - 1295 (1992)
Update date:2022-09-26
Topics: Antagonist Lipophilicity IC50 Pharmacophore binding affinity Steric Effects Structure-Activity Relationship (SAR) Cyclohexyl Agonist Muscarinic receptor Selectivity Index Ki (Inhibition constant)
Leader, Haim
Gordon, Richard K.
Baumgold, Jesse
Boyd, Victoria L.
Newman, Amy H.
et al.
A series of aprophen <(N,N-diethylamino)ethyl 2,2-diphenylpropionate> analogues, called cylexphenes, were synthesized with alterations in (1) the chain length of the amine portion of the ester, (2) the alkyl groups on the amino alcohol and (3) a cyclohexy
View Morewebsite:http://www.antimex.com
Contact:0086-21-50563169
Address:Room1027,No.Jinyu Road,Pudong
Guangzhou Probig Fine Chemical Co., Ltd.
Contact:020-86297874
Address:No.2, 1/F, No.20, Hetai Road,Hebian Village, Baiyun District,Guangzhou,China
Xi'an yuanfar international trade company
website:https://www.yuanfarchemical.com
Contact:86-029-88745613 ext 828
Address:Floor19th ,B Building, Oak Block,No.36 South Fenghui Road, Dev. Zone of High-Tech Ind.,Xi’an, China
Yangzhou Zhongbao Pharmaceutical Co.,Ltd
Contact:+86-514-88290838
Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
RongCheng K&S Chemical Co.,Ltd
Contact:0631-7336369
Address:rongcheng ,shandong province china
Doi:10.1002/ejoc.201701235
(2017)Doi:10.1080/00397910500182606
(2005)Doi:10.1021/jo0355799
(2004)Doi:10.1021/ja020816v
(2002)Doi:10.1016/S0040-4020(01)93888-8
(1965)Doi:10.1021/acs.biochem.9b00003
(2019)
