Biocatalyzed preparation of the optically enriched stereoisomers of 4-methyl-2-phenyl-tetrahydro-2H-pyran (Doremox)

DOI: 10.1139/v02-042

Source and publish data:

Canadian Journal of Chemistry p. 714 - 723 (2002)

Update date:2022-08-05

Topics:

Authors:

Brenna, Elisabetta

Fuganti, Claudio

Ronzani, Sabrina

Serra, Stefano

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Article abstract of DOI:10.1139/v02-042

The four stereoisomers of the rose oxide analogue Doremox were prepared in enantiomerically enriched form by enantiospecific bakers' yeast reduction of suitable derivatives and by lipase-mediated kinetic resolution of diol precursors.

Full text of DOI:10.1139/v02-042

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