Bioscience, Biotechnology and Biochemistry p. 2283 - 2290 (2007)
Update date:2022-08-04
Topics:
Yamauchi, Satoshi
Sugahara, Takuya
Matsugi, Junko
Someya, Tatsushi
Masuda, Toshiya
Kishida, Taro
Akiyama, Koichi
Maruyama, Masafumi
The effect of the benzylic structure of lignan on antioxidant activity was evaluated. Secoisolariciresinol (1) and 3,4-bis(4-hydroxy-3-methoxybenzyl) tetrahydrofuran (2), which have two secondary benzylic positions without oxygen, showed the highest antioxidant activity. Optically active verrucosin (4) was synthesized for the first time in this experiment.
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Doi:10.1177/1747519820960692
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