Development of Radioiodinated Benzofuran Derivatives for in Vivo Imaging of Prion Deposits in the Brain

DOI: 10.1021/acsinfecdis.8b00184

Source and publish data:

ACS Infectious Diseases p. 2003 - 2013 (2019)

Update date:2022-08-15

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Authors:

Atarashi, Ryuichiro

Fuchigami, Takeshi

Haratake, Mamoru

Kawasaki, Masao

Koyama, Ryusuke

Nakagaki, Takehiro

Nakaie, Mari

Nakayama, Morio

Nishida, Noriyuki

Ono, Masahiro

Sano, Kazunori

Yoshida, Sakura

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Article abstract of DOI:10.1021/acsinfecdis.8b00184

Prion diseases are fatal neurodegenerative disorders associated with the deposition of abnormal prion protein aggregates (PrP^Sc) in the brain tissue. Here, we report the development of ¹²⁵I-labeled iodobenzofuran (IBF) derivatives as

Full text of DOI:10.1021/acsinfecdis.8b00184

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