THE UNUSUAL CYCLIC PRODUCTS FROM TETRA- AND PENTA-PEPTIDES OF α-METHYLALANINE

DOI: 10.1016/S0040-4020(01)96438-5

Source and publish data:

Tetrahedron p. 451 - 454 (1985)

Update date:2022-08-05

Topics: Characterization Yield Stereochemistry Intramolecular cyclization Mass spectrometry (MS) Conformation High-performance liquid chromatography (HPLC) Cyclization reaction Nuclear Magnetic Resonance (NMR) Purification Circular Dichroism (CD) Tetrapeptide Reaction Monitoring Solid-Phase Peptide Synthesis (SPPS) Chirality Peptide bond pentapeptide Cyclic Product Non-proteinogenic amino acid

Authors:

Ali, M. Y.

Khatun, Anowara

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Article abstract of DOI:10.1016/S0040-4020(01)96438-5

Tetra- and pentapeptides of α-methylalanine give with PCl5, SOCl2 etc. intermediates which, with or without loss of amino acids, lead to bi- and tricyclic products containing imidazole and piperazine rings through different routes.

Full text of DOI:10.1016/S0040-4020(01)96438-5

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