Tetrahedron Letters p. 2845 - 2848 (1994)
Update date:2022-09-26
Topics:
Kearns, Jeff
Kayser, Margaret
A simple synthesis of (2R,3S)-phenylisoserine, a precursor of the C-13 side chain of Taxol (paclitaxel), utilising yeast-catalyzed reduction to generate a second chiral centre is reported.This short enantioselective series of transformations can be readily adapted to large scale production of a variety of N-substituted paclitaxel analogues.
View MoreContact:(1) 206-3550089
Address:5115 NE 8TH PL, Renton, WA 98059 USA
Jiangsu Allyrise Pharmaceutical Co., Ltd.(expird)
Contact:+86-523-86818997
Address:Taizhou,Jiangsu Province,CHINA
website:http://www.cartoonchem.com/
Contact:+86-25-58074918
Address:Room 2109, RuiHua Business Center,315 South ZhongShan Road, Nanjing 210001, China
Zhejiang Linhai Xinhua Chemicals Factory
Contact:0086-13661858911
Address:Xunqiao Development Zone, Linhai, Zhejiang, China
Taizhou Shengxing Chempharm Co.,Ltd
Contact:+86-576-88516600
Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Doi:10.1021/jm00227a600
(1976)Doi:10.1021/ja00824a041
(1974)Doi:10.1016/S0957-4166(02)00838-8
(2003)Doi:10.1021/acs.orglett.9b01762
(2019)Doi:10.1016/j.inoche.2014.02.017
(2014)Doi:10.1021/jo01141a007
(1951)
